The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Behind every great day is a great night at the Comfort Inn and Suites Clemson - University Area hotel in Clemson, SC near Clemson University. This smoke-free hotel is near destinations like Brooks Center for the Performing Arts, T. Ed Garrison Arena, Ashtabula Plantation, Woodburn Plantation and Lake Hartwell. Enjoy amenities like free hot breakfast, free WiFi, laundry facilities, business center, banquet rooms and access to copy and fax machines. Rooms include a flat-screen TV, hair dryer, iron and ironing board. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.