Tucked between College Avenue and Sloan Street in downtown Clemson, South Carolina, The Shepherd Hotel awaits. At the Shepherd Hotel, we believe that life is about supporting those we love and those that need our love. We believe that home is more than just a location-- it's a feeling. The Shepherd Hotel encapsulates the heart of the Clemson community, incorporating an eclectic mix of cozy, transitional furnishings and design, original work from local artists, and some very special employees.