The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Rest and refresh at the pet-friendly Comfort Inn and Suites Greenville I-70 hotel in Greenville, IL. We are near Greenville College, DeMoulin Museum and Greenville Regional Hospital. Amenities include free WiFi, free ample parking, free hot breakfast, meeting room, fitness and business centers, guest laundry facilities and an indoor heated pool. Behind every great day is a great night in your guest room, which features a refrigerator, microwave, coffee maker, hair dryer, iron and ironing board. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program. Limit of 2 40-lb. pets/room, USD10/pet/night. USD50 refundable deposit required of cash-paying guests at check-in.