Welcome to the Hampton Inn Lexington-Historic District hotel in Historic Lexington, Virginia. This unique hotel brings to life 170 years of history. It is located on a seven acre park-like setting within walking distance of the Lexington Historic District and local attractions. As you enter the city of Lexington, Virginia this is your first site of the majestic manor house Col. Alto, built in 1827, just 2.5 miles from Interstate 81 at exit 188B. This Hampton Inn Lexington hotel is listed on the National Register of Historic Places in Virginia. The Col. Alto Mansion is the starting point for your unique Virginia hospitality experience.