The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more for you money at the Quality Inn and Suites Santee I-95 hotel in Santee, SC, ideally located off Interstate 95. We are focused on giving you the best rates and amenities so you can focus on the reason you travel to the region. We offer meeting space for up to 300 people, free WFi, and a free hot breakfast. Enjoy casual dining in in our bar and grill, too. At the end of your day, our inviting guest rooms have everything you need for the night, including coffee makers, hair dryers, irons with boards and TVs. Some rooms have microwaves and refrigerators. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.