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This combination medication is utilized for a brief timeframe (typically under 10 days) to help mitigate moderate to serious agony. It contains an opioid (narcotic) torment reliever (hydrocodone) and a nonsteroidal mitigating drug-NSAID (ibuprofen). Hydrocodone works in the brain to change how your body feels and reacts to torment. Ibuprofen diminishes agony and fever.