About Ann Arbor Comprehensive Treatment Center in Ann Arbor, MI Located in Ann Arbor, Michigan, Ann Arbor Comprehensive Treatment Center (CTC) provides medication-assisted treatment (MAT) for adults age 18 and older of all genders who are struggling with opioid use disorder. MAT is a research-backed form of treatment that uses both prescription medication and therapeutic components to help people achieve successful recovery from opioid addiction. Many methadone clinics only provide one type of medication as part of treatment, but our Ann Arbor center offers methadone, Suboxone, naltrexone, and buprenorphine.