The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get rested and ready for anything at the Comfort Inn Edwardsville - St. Louis hotel in Edwardsville, IL near Gateway International Raceway. We are located off of Interstate 270 near Anheuser-Busch World Headquarters, Casino Queen Riverboat Casino, Gateway Arch Riverfront and the Saint Louis Science Center. Amenities you can count on include free breakfast, free WiFi, an indoor pool, access to copy and fax services, two conference rooms and free weekday newspaper. Rooms include TVs and coffee makers in addition to standard room amenities. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.