The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get rested and ready for anything when you stay at our pet-friendly Comfort Inn Kirksville hotel in Kirksville, Missouri. Our smoke-free hotel is close to the Thousand Hills State Park, A.T. Still University, Missouri Department of Conservation, Kraft and Stokes Stadium. Each guest can enjoy our free breakfast, free WiFi, exercise room and business center. Each comfy guest room is furnished with a hair dryer, coffee maker, TV and premium bedding. Start earning rewards points today when you sign up for our Choice Privileges program. Some amenities may require an additional cost.