The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Behind every great day at the Comfort Inn South hotel in Medford, OR is a great night. We are located off Interstate 5 near Harry and Davids Country Village, Rogue Valley International-Medford Airport, Southern Oregon University and more. Crater Lake National Park and Mount Ashland Ski Area are a short drive away. Hotel amenities include free breakfast, free WiFi, an indoor pool, an exercise room and much more, including copy and fax services. Relax in your guest room which includes a refrigerator, microwave, coffee maker, hair dryer, iron and ironing board. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.