About Temecula Comprehensive Treatment Center in Murietta, CA Temecula Comprehensive Treatment Center provides outpatient treatment to adults age 18 and older in the Murietta, California, area who have been struggling with opioid addiction. Opioid addiction treatment at our center in Murietta includes prescription medication and counseling. This combination, which is known as medication-assisted treatment (MAT), has been closely studied for decades, and it has a documented history of effectiveness.