At Papa Johns Pizza in Sikeston, MO, it’s our goal to always bring you Better Ingredients. Better Pizza. Whether it's our signature sauce, toppings, or fresh, original dough, we invest in our ingredients to ensure you have the best Sikeston pizza for any occasion. Call us for pizza delivery in Sikeston or stop by 225 NORTH MAIN STREET for carryout to order the best pizza in Sikeston, along with breadsticks, wings, and more!