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Truvada and other antiretroviral drugs containing the active ingredient tenofovir disproxil increase the risk of bone density loss, fracture, renal impairment, and kidney failure. Among the most popular HIV drugs in the world, Truvada has serious side effects that cause injury and permanent damage to persons already suffering from HIV. A safer version of tenofovir, known as TAF, is an effective antiretroviral that does not pose the same risk for kidney problems and bone density loss.
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