De La Salle Santiago Zobel School is a member of De La Salle Philippines (DLSP), a new district-wide network of seventeen Lasallian schools in the country. The school was established on March 29, 1978 to meet the objective of moving the elementary department of De La Salle University ? Manila to a more conducive and suitable learning environment with a high school department to assure grade school graduates of placement for secondary education.